diff --git a/uncompyle6/__init__.py b/uncompyle6/__init__.py
index ae599115..a08bb78b 100644
--- a/uncompyle6/__init__.py
+++ b/uncompyle6/__init__.py
@@ -41,6 +41,8 @@ PYTHON3 = (sys.version_info >= (3, 0))
 PYTHON_VERSION = sys.version_info[0] + (sys.version_info[1] / 10.0)
 PYTHON_VERSION_STR  = "%s.%s" % (sys.version_info[0], sys.version_info[1])
 
+IS_PYPY = '__pypy__' in sys.builtin_module_names
+
 sys.setrecursionlimit(5000)
 
 def check_python_version(program):
diff --git a/uncompyle6/opcodes/opcode_27.py b/uncompyle6/opcodes/opcode_27.py
index 0566bf17..b4dbba3f 100755
--- a/uncompyle6/opcodes/opcode_27.py
+++ b/uncompyle6/opcodes/opcode_27.py
@@ -202,10 +202,19 @@ EXTENDED_ARG = 145
 def_op('SET_ADD', 146)
 def_op('MAP_ADD', 147)
 
+from uncompyle6 import IS_PYPY
+if IS_PYPY:
+    def_op('LOOKUP_METHOD', 201)
+    def_op('CALL_METHOD', 202)
+    def_op('BUILD_LIST_FROM_ARG', 203)
+    def_op('JUMP_IF_NOT_DEBUG', 204)
+
 updateGlobal()
 del def_op, name_op, jrel_op, jabs_op
 
 from uncompyle6 import PYTHON_VERSION
 if PYTHON_VERSION == 2.7:
     import dis
+    # print(dis.opmap.items())
+    print(set(dis.opmap.items()) - set(opmap.items()))
     assert all(item in opmap.items() for item in dis.opmap.items())